(March 1, 2010) New York, NY – Award-winning actress and heart health advocate, Andie MacDowell, and Richard H. Carmona, M.D., M.P.H., FACS, 17^th Surgeon General of the United States (2002-2006), have partnered to highlight the importance of effective communication between patients and health care professionals (HCPs) by introducing an innovative program: Time to Talk CARDIO – Creating A Real Dialogue In the Office.

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Cambridge, MA, US – February 26, 2010 – Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announced today that the U.S. Food and Drug Administration (FDA) has granted marketing approval for VPRIV, a human cell line derived enzyme replacement therapy (ERT) for the long-term treatment of Type 1 Gaucher disease in pediatric and adult patients. The FDA designated VPRIV for Priority Review and granted marketing approval in just 6 months.

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